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Webb7 apr. 2024 · B-cell lymphoma 6 (BCL6) is a transcriptional repressor and oncogenic driver of diffuse large B-cell lymphoma (DLBCL). Here, we report the optimization of our previously reported tricyclic quinolinone series for the inhibition of BCL6. We sought to improve the cellular potency and in vivo exposure of the non-degrading isomer, … Webb15 nov. 2024 · Genealogy profile for Anne Pleydell-Bouverie (Duncombe), Countess of Radnor can learner drivers go on the motorway
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