網頁2014年1月1日 · This differential expression of STEAP1 may point to its putative roles in prostate cancer, enabling cellular communication and facilitating prostate cancer … As EVs carry proteins representative of their cell of origin and STEAP1 expression has been reported to be elevated in PCa relative to healthy prostate tissue, this elevated expression of STEAP1 may be reflected by EVs present in biological fluids such as blood. To determine if STEAP1 could be detected on … 查看更多內容 Following identification and characterization of STEAP1-positive EVs from SEC isolated fractions of plasma, whole, unpurified, plasma from heathy (n = 55) … 查看更多內容 To determine if STEAP1 levels associated with disease severity, STEAP1 levels were analyzed by Gleason Group. Individuals with an initial diagnosis of … 查看更多內容
Abstract 4396: TROP2 expression in non-small cell lung cancer
網頁2014年12月1日 · Antibodies and antibody-drug conjugates targeting the cell surface protein 6 transmembrane epithelial antigen of prostate 1 (STEAP1) are in early clinical … 網頁2014年9月24日 · Quantitative analysis of STEAP1 and 2 gene expression were statistically significantly associated with the metastatic cell lines DU145 and PC3 as compared to the normal prostate epithelial cell line, PNT2. This expression pattern was also mirrored at the protein level in the cells. born in a barn songs
Cancer Drug Target: STEAP-1 Sino Biological
網頁2024年8月20日 · Six-Transmembrane Epithelial Antigen of the Prostate 1–4 (STEAP1–4) compose a family of metalloproteinases involved in iron and copper homeostasis and other cellular processes. Thus far, five homologs are known: STEAP1, STEAP1B, STEAP2, STEAP3, and STEAP4. In prostate cancer, STEAP1, STEAP2, … 網頁2012年10月11日 · STEAP1 is over-expressed in several types of tumors, especially prostate cancer, where it is localized in the plasma membrane of epithelial cells, at cell-cell junctions. Its role in prostate carcinogenesis and its regulation in … 網頁2 天前 · Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface antigen for therapeutic targeting in prostate cancer. Here, we report broad expression … haven practice brighton